torsdag 30. september 2010

Biochemistry of viruses

Virology: an approach to HIV-treatment - an idea/theory.

Viruses contain a lot of proteins in their capsids and envelopes: N-CR-C-N-CR-C-N-CR-C-N-CR-C … and so on. These protein chains are densely packed. They can be dissolved by short-chain fatty acids, e.g. the four-carbon butyric acid: C-C-C-COOH. This acid is small enough to creep in between the protein chains, it will intermingle and get locked between the R-groups in the protein chains. The acid will act as a soap molecule, make fractures and fringe, puncture/implode the viruses. Beside acting as an amphipathic soap molecule in the fat/protein-intersection, the butyric acid and its related molecules will neutralize the viruses.

The stuff will hit the viruses like arrows and break them up – like millions of tiny wedges. Butterfat contains a broad range of fatty acids of varying lengths, which are bound up in triglycerides. Maybe around 10% have less than 12 carbon atoms. Butyric acid alone constitutes 3-4%.
When butter is boiled in base (HO-), the fatty acids get released (saponification). When I boiled butter in sodium bicarbonate (NaHCO3 – baking soda) and water, I got a cocktail of water-soluble, short-chain, free fatty acids. The cocktail showed very promising features in dissolving stacked proteins. When drinking this in sufficient amounts, some of the free fatty acids will avoid getting built into chylomicrons in the enterocytes. Thus they will be interspersed in blood and lymph, and hopefully they can emulsify/dissolve viruses.

A possible side-effect is water retention in interstitial fluid due to Gibbs-Donnan effect and osmotic pressure.
Delayed blood clotting/anti-thrombosis effect and increased bleeding due to dissolving of coagulation factors and cholesterol/fat is maybe another considerable aspect.

PS! Virusinfections and cancers are often correlated, with stacked-proteins-pathogenesis as a common trait, so it should be tried in cancer therapy too.
Even in Alzheimer`s disease there are characteristic stacked proteins (amyloids) and plaques, so this approach can be far-reaching!

Recipe:
One spoon of butter, two spoons of baking soda and three spoons of water boiled to the top in a small pot will do the trick.

Invented and written by:


Ottar Stensvold

Molde
Norway

ottarstensvold@hotmail.com

http://ottarstensvold.wordpress.com/

1 kommentar:

  1. Some relevant links:

    This article shows the virucidal effect of lipids after only 30 minutes of incubation:

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC174645

    Inactivation of enveloped viruses in human bodily fluids by purified lipids:

    http://www.ncbi.nlm.nih.gov/m/pubmed/8030973

    Virucidal effect of lipids on visna virus, a lentivirus related to HIV:

    http://www.ncbi.nlm.nih.gov/m/pubmed/16388394/?

    Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies:
    http://www.sciencedirect.com/science/article/pii/S0024320598002793

    Protective activity of monoacetone glucose 3-butyrate, prodrug of n-butyric acid, against the fatal effect of encephalomyocarditis virus in mice:
    http://www.ncbi.nlm.nih.gov/m/pubmed/1313734

    Electron-microscopic studies show that the envelope of vesicular stomatitis virus (VSV) is completely destroyed by linoleic acid (18:2):

    http://books.google.no/books?id=6ZepRgMaa2gC&pg=PT143&lpg=

    Butter contains linoleic acid:

    http://en.m.wikipedia.org/wiki/Linoleic_acid#section_1

    http://en.m.wikipedia.org/wiki/Butterfat#section_1

    http://en.m.wikipedia.org/wiki/Sunflower_butter#section_3

    Butyrate strains viruses in action within days:

    http://www.ncbi.nlm.nih.gov/m/pubmed/2986799

    Inactivation of visna virus and other enveloped viruses by free fatty acids and monoglycerides:

    http://www.ncbi.nlm.nih.gov/m/pubmed/8030974

    Butyric acid destroys the protein-laden erythrocytes:

    http://www.ncbi.nlm.nih.gov/m/pubmed/1810341

    (working for 60 minutes and with mechanical stress/centrifugation)

    The old butyric acid test for syphilis shows turbidity when butyric acid binds to serum proteins:

    http://archive.org/stream/39002010637842.

    Degradation of tobacco mosaic virus with acetic acid:

    http://www.sciencedirect.com/science/article/pii/0042682257900387

    Degradation of influenza viruses with acetic acid:

    http://goo.gl/wUd2wL

    http://www.ncbi.nlm.nih.gov/m/pubmed/19439628/?

    Acetic acid as a solvent for erythrocyte membrane proteins:

    http://www.sciencedirect.com/science/article/pii/0005273671900290

    Red blood cells are lysed with 2% acetic acid:

    http://www.ncbi.nlm.nih.gov/m/pubmed/8513697

    The effect of pH on the inhibition of bacterial growth by physiological concentrations of butyric acid: implications for neonates fed on suckled milk:

    http://ukpmc.ac.uk/abstract/MED/9717513

    Inactivation of avian influenza virus using common detergents and chemicals:

    http://www.ncbi.nlm.nih.gov/m/pubmed/18459307

    Breastmilk found to destroy HIV:

    http://www.naturalnews.com/036382_breast_milk_AIDS_HIV.html

    SvarSlett