onsdag 3. desember 2014

Booster Sports Drops




I present here the nutrient I have developed, for general info in the first place.

I think there is a great opportunity in applying energy to the immune system. The stuff described here under (polyacetylated carbohydrates / sugar derivatives found in plants) will as all nutrients first encounter the immune cells when taken up to blood. It will even directly fuel the immune cells by diffusion into the mucous membranes in the lymphatic tissue in and around the tonsils.

It thus implies great opportunities not only by means of nutritional energy supply, but also by means of worldwide distribution and sales. 

"and the leaves of the tree were for the healing of the nations" - Revelation 22:2

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Booster Sports Drops Rum is made of sugar, vinegar and rum aroma.

Colour may vary. Store cold and dry.


the booster sports drops 
natural nutraceutical boooooster

Ladies and gentlemen, let me introduce the world-class nutraceutical: The Booster Sports Drops. It`s an invention based on the precious experience made by the sugar plantation slaves. During their suffering in the heat of the day, they drank / ate raw cane sugar and experienced an enduring stream of energy. This made them capable to bear inhuman burdens of work. The secret lay in the acetylated sugar compounds in the canes. I will honor the memory of these good people and prevent slavery and unfair treatment from happening again. Therefore, I invented The Booster Sports Drops. I discovered this kind of sugar compound that can access the cells in the body without the help of insulin. Insulin is a hormone that in a complex receptor-ligand-cascade chain lets the cells express glucose transporters as GLUT-4 (and other transporter / receptor proteins like for instance LDL-receptors) in their membranes, e.g. muscle cells. This sugar compound is less polar and more branched than ordinary glucose, and it thus more easily bind to the unpolar cell membrane (softens it). At the interface of the cell membranes, it also solutes glucose. The cells will simply engulf this by endocytosis. Other nutrients, as for example cholesterol (in LDL) will also be taken up in the process. This scavenges the blood, lowering the glucose rate and the cholesterol rate in the blood, - key factors for a healthy life! It thus functions as a generic insulin / glucose transporter, and might help diabetics among others. The sugar compound in the Booster Sports Drops promotes endocytosis. Once taken up by the cells, the complex carbohydrates (in endosomes) will be attached by lysosomes in the cytoplasm. The acidic (low pH) lysosome vesicles contain acid hydrolases. These enzymes hydrolyse the sugar compounds and release new functional molecules, namely acetic acids which otherwise can`t enter cells in such packages. In a normal human cell, there are around 2000 mitochondria (more in muscle cells). The mitochondria are the energy factories of the body. Acetic acid enters the mitochondria and goes directly into the citric acid cycle and a high yield, O2-consuming energy production. This process ignites the whole body, and keeps the metabolism, the burning of nutrients - "the wheel of life" - in motion. Since the sugar in the Booster Sports Drops are evenly distributed and don`t discriminate between cells, it restores a physiological balance. Acetylation increases bioavailability and crossing of the blood-brain barrier. Luckily, it let the most healthy cells utilize, thrive and work. One can for instance assume that cancer cells, which have an insufficient respiratory chain, and mainly survive by the incomplete, anaerobic glycolysis (breakdown of glucose) which occurs in the cytoplasm, get suppressed when other healthy nearby cells thrive by respiration (i.e. immune cells). And maybe the cancer cells lack the efficient lysosomal machinery to avoid engorgement / molecule overload / sensitivity for metabolism. The same can be true for other diseases as well (e.g. bacterial cells). And consider treatment of diseases which occur because of too strong immune reactions: overactive autoimmune phagocytes can be kept busy by the drug (complex sugar derivatives) instead of destroying surrounding tissue for food / debris (e.g. arthritis and allergy / asthma). Triggering of naive regulatory T cells is another possibility. There are other benefits as well: it makes the endothel of the circulatory system more resilient, and can decrease blood pressure by ca. 5%. And maybe deployment in membranes of erythrocytes and neurons will increase flexibility and give a more rapid exchange of CO2 / O2 and neurotransmitters. Actually, the nervous system use one-third of the body`s energy and should benefit from any good sugar-supply! The Booster Sports Drops is the ideal drops for any high-performer, whether it`s the brain worker, the athlete or the creative artist. It lights the fire! The way these nutraceutical carbohydrate compounds act in the body have always been naturally occurring. There are also drugs, like auranofin (Ridaura) or aspirin that contains ester-bonded acetic acid, and which mechanism of action has not been fully revealed yet. Along with the slaves, it`s also appropriate to mention Jesus who got the strengthening vinegar when suffering at the cross (John 19). The healing energy source is now revealed, elucidated and fortified! The Booster Sports Drops does not contain alcohol, but it has a wonderful blended taste of Jamaica rum and caramel. And the flavour? - It`s like dew beside a river in the Norwegian spring forest. 

Please search the web for explanatory videos and pictures of cell membranes, endocytosis, auranofin molecule, aspirin molecule, glucose molecule etc. 

- see this 35-second video about endocytosis: 
http://www.youtube.com/watch?v=4gLtk8Yc1Zc 

A three-cyclic sugar / carbohydrate compound, with acetic acid attached, is probably present in the Booster Sports Drops. (Picture shown in frontpage heading) 

Ac=Acetate=CH3CO2- get dynamically released in the cytoplasm by the help of acid hydrolases (esterases). 

Polyphenols, like for instance resveratrol (found in red wine) or curcumin (found in turmeric), or quercetin - a flavonoid in fruits / apples and other polyphenols (e.g in green tea), can maybe act upon cell membranes in a similar fashion as the polycyclic molecule in the Booster Sports Drops. Please search the web for info about resveratrol, curcumin, quercetin and polyphenols / flavonoids / antioxidants. See also cinnamaldehyde / cinnamon in this regard.

Picture of polyacetylated a complex carbohydrate molecule are shown in frontpage heading. Similar molecules are probably present in the Booster Sports Drops.

Loosely bound acetic acid is ready to be released in cells!

Please search the internet for info about glucose transporters.
The sugar derivative in the Booster Sports Drops can interact with / substitute / supplement the glucose transporters. Note that there are also other isoforms of glucose transporters which are not dependent upon insulin for their expression (e.g. in brain cells). 

Regarding sugar cane plantation slaves, see picture: 
http://www.movinghere.org.uk/galleries/roots/caribbean/images/S0001575.jpg

Mitochondrion - see picture: 
http://www.mda.org/publications/images/pamphlet_mitochondria_diag.jpg
The end product adenosine triphosphate (ATP) in mitochondria is an energy carrier molecule which play a key role in cell communication and activity. The Booster Sports Drops is quickly converted into ATP. The oxidative phosphorylation to form ATP occurs in the electron transport chain where oxygen (1/2 O2) is reduced to form water, H2O, by the joining of two protons (2H+) and two electrons (2e-). Please search the web for info about the citric acid cycle! The pivotal citric acid cycle takes place in mitochondria. The quick, initiating, igniting, efficient fuel in this cycle is acetate or acetyl (CH3CO): Acetate + Coenzyme A (CoA-SH) + ATP => Acetyl-CoA + ADP. The stuff (free acetate) bypasses both glycolysis and the extremely complicated pyruvate dehydrogenase complex by the help of the enzyme Acetyl-CoA Synthetase to become Acetyl-CoA!

Written by / invented by Ottar Stensvold

fredag 10. oktober 2014

Therapeutic HIV vaccine - RNA viruses - Ebola


Enzymatic cleavage of viral genomes: hydrolysis interchangeable with ammonolysis in a kind of nitrogen fixation.

This could also be relevant for Ebola, which also is a single-stranded RNA virus:

Therapeutic HIV vaccine

The body's initial "vaccine-reaction" against HIV could be prolonged if the viruses were inactivated. In comparison, the poliovirus can be inactivated by cleavage of its RNA by ammonia. Hopefully, the same can be true for HIV. Both viruses contain single-stranded RNA and hydrolytic proteases. Perhaps the proteases perform (catalyse) ammonolysis of the phosphodiester bonds in RNA, and so cut the strands. HIV has even RNase H which is specialized in breaking RNA strands. I guess there are proteins with nuclease activity also in the Ebola viruses, e.g. the nucleoprotein (NP). Maybe even coiled, viral RNA can work on itself as an ammonolytic ribozyme. The phosphorus/phosphate (PO4-) in RNA repels water more than it repels ammonia, and is thus favoring ammonolysis over hydrolysis. (NH3 is a stronger nucleophile and a slightly lighter molecule than H2O).
The tight encapsulation/packing of RNA in the viruses will promote the ammonolysis process. It brings the 2' hydroxyl group close to the phosphorus, catalysing breakage of the phosphodiester bonds. There is high inward osmotic pressure in viruses. The hydrophobic cores in the ribonucleoproteins will attract ammonia.
(The Ebola viruses are extra prone to breakage during mechanical stress in vivo because of their long, rod-shaped forms).
And the host cells use RNases to hydrolyse foreign RNA. Maybe the RNases switch to ammonolysis when ammonia is available, and thereby speed up this defense.
In this regard, inhalation of ammonia could be a way to destroy HIV and other RNA viruses in blood and tissue.

Written by:

Ottar Stensvold

Molde 
Norway

Principle of hydrolysis:

fredag 22. august 2014

Cholesterol might ease Ebola infections


Picture of Ebola virus entry into cell from 
http://www.einstein.yu.edu/faculty/10768/kartik-chandran/
Picture from http://www.nature.com/nrm/journal/v2/n9/fig_tab/nrm0901_657a_F2.html
If you flip-flop cholesterol (top), you can see it resembles benzylpiperazine adamantane diamide, a known NPC1 inhibitor (bottom)


I suggest Gogel Mogel could be beneficial for Ebola patients, simply by blocking Niemann–Pick C1 (NPC1), a cholesterol transporter protein, by cholesterol. The Ebola virus uses NPC1 for cell entry, and when cholesterol blocks this protein the viruses' entry into the cytoplasm will be impeded. Then there will be an increased virus accumulation and degradation in lysosomes. Raw eggs in Gogel Mogel will deliver much free, easy-absorbable cholesterol, and in addition they will deliver free amino acids, which are essential for quick synthesis of antibodies. 


See excerpts from Wikipedia below. 

Sincerely, 

Ottar Stensvold 

Molde
Norway

Gogel Mogel:
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Preparation

The dish consists of raw egg yolks and sugar, beaten and ground until they form a creamy texture, with no discernible grains of sugar. In modern kitchens, it is often mixed in a blender until it changes color and becomes thick. A classic single Gogl-Mogl portion is made from two egg yolks and three teaspoons of sugar beaten into a cream-like dish. Variations can be made by adding chocolate, vodka, rum, honey, vanilla, lemon juice, raisins, whipped cream, or a number of other ingredients based on one's own taste preferences. A Polish variation includes the addition of orange juice, creating a taste similar to an Orange Julius.

Uses

Gogel Mogel is often prepared as a transition food for babies moving from a cereal diet to one that includes eggs and other soft foods. It is also a folk medicine used for treating colds or flu, particularly chest colds and laryngitis. Gogle-mogle is ranked highly among other traditional cold remedies such as Grandma's chicken soup. The baby transition recipe includes raw eggs and sugar which in spite of its widespread use in Russia, is a health risk to young children due to possible contraction of Salmonella.
The traditional usage of Gogle Mogle as a home remedy for treating a sore throat is supported by research done in Israel.[5][6] The simplest form of preparation as a remedy is with no egg, but only honey added to warm milk. More commonly, a single raw egg is added to a cup of warm milk and mixed with a tablespoon of honey.

Ebola:
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Entry

There are two candidates for host cell entry proteins. The first is the host-encoded Niemann–Pick C1 (NPC1), a cholesterol transporter protein, which appears to be essential for entry of Ebola virions into the host cell, and for its ultimate replication.[11][12] In one study, mice that were heterozygous for NPC1 were shown to be protected from lethal challenge with mouse-adapted Ebola virus.[11] In another study, small molecules were shown to inhibit Ebola virus infection by preventing viral envelope glycoprotein (GP) from binding to NPC1.[12][13] Hence, NPC1 was shown to be critical to entry of this filovirus, because it mediates infection by binding directly to viral GP.
When cells from Niemann Pick Type C patients lacking this transporter were exposed to Ebola virus in the laboratory, the cells survived and appeared impervious to the virus, further indicating that Ebola relies on NPC1 to enter cells; [citation needed] mutations in the NPC1 gene in humans were conjectured as a possible mode to make some individuals resistant to this deadly viral disease. [citation needed][speculation?] The same studies described similar results regarding NPC1's role in virus entry for Marburg virus, a related filovirus. A further study has also presented evidence that NPC1 is critical receptor mediating Ebola infection via its direct binding to the viral GP, and that it is the second "lysosomal" domain of NPC1 that mediates this binding.[14]
The second candidate is TIM-1 (aka HAVCR1).[15] TIM-1 was shown to bind to the receptor binding domain of the EBOV glycoprotein, to increase the receptivity of Vero cells. Silencing its effect with siRNA prevented infection of Vero cells. TIM1 is expressed in tissues known to be seriously impacted by EBOV lysis (trachea, cornea, and conjunctiva). A monoclonal antibody against the IgV domain of TIM-1, ARD5, blocked EBOV binding and infection.
Together, these studies suggest NPC1 and TIM-1 may be potential therapeutic targets for an Ebola anti-viral drug and as a basis for a rapid field diagnostic assay. [citation needed]